Sumatriptan (intranasal route of administration) for acute migraine attacks in adults

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[Sumatriptan plus naproxen for acute migraine attacks in adults].

It is of great importance to improve acute treatment of migraine attacks. Non-steroidal anti-inflammatory drugs (NSAID) and triptans have different anti-nociceptive effects, so a combination of these could theoretically lead to more effective acute migraine treatment. A recent meta-analysis investigated the combined effect of sumatriptan and naproxen and found it to be more effective than sumat...

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Intranasal sumatriptan for migraine in children.

QUESTION I am seeing more and more children and adolescents with headaches that can be defined as migraine headache. I have read about intranasal sumatriptan as an abortive therapy. Is this an effective treatment? ANSWER Acute migraine headache among children and adolescents is common and treatment is challenging. Intranasal sumatriptan is a safe and mostly effective option for children and a...

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Comparison between Intravenous Sodium Valproate and Subcutaneous Sumatriptan for Treatment of Acute Migraine Attacks; Double-Blind Randomized Clinical Trial

Background: Sodium valproate (SV) has been approved for migraine prophylaxis and its intravenous form is used to treat acute migraine attacks. We compared the efficacy and safety of intravenous SV and subcutaneous Sumatriptan in managing acute migraine attacks. Methods: This double-blind randomized clinical trial divided 90 patients into two groups: one group received 400 mg of intravenous SV a...

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Treatment of acute migraine with subcutaneous sumatriptan.

Sumatriptan succinate, a 5-HT1D receptor agonist, constricts human cranial arteries. Two parallel-group trials for treatment of acute migraines were conducted in the United States. Adult patients were randomized and given either 6 mg of sumatriptan succinate subcutaneously (n = 734) or placebo (n = 370). At 1 hour, sumatriptan was significantly more effective than placebo in reducing moderate o...

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comparison between intravenous sodium valproate and subcutaneous sumatriptan for treatment of acute migraine attacks; double-blind randomized clinical trial

background: sodium valproate (sv) has been approved for migraine prophylaxis and its intravenous form is used to treat acute migraine attacks. we compared the efficacy and safety of intravenous sv and subcutaneous sumatriptan in managing acute migraine attacks. methods: this double-blind randomized clinical trial divided 90 patients into two groups: one group received 400 mg of intravenous sv a...

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ژورنال

عنوان ژورنال: Cochrane Database of Systematic Reviews

سال: 2012

ISSN: 1465-1858

DOI: 10.1002/14651858.cd009663